Lanean...
The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations
Lamin B receptor (LBR) is a polytopic membrane protein residing in the inner nuclear membrane in association with the nuclear lamina. We demonstrate that human LBR is essential for cholesterol synthesis. LBR mutant derivatives implicated in Greenberg skeletal dysplasia or Pelger-Huët anomaly fail to...
Gorde:
| Argitaratua izan da: | eLife |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
eLife Sciences Publications, Ltd
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951196/ https://ncbi.nlm.nih.gov/pubmed/27336722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16011 |
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