The effect of a HFD on mitochondrial metabolism depends on nutritional state and mTORC1 activation

Dysregulated mitochondrial metabolism during hepatic insulin resistance may contribute to pathophysiologies ranging from elevated glucose production to hepatocellular oxidative stress and inflammation. Since obesity impairs insulin action but paradoxically activates mTORC1, we tested whether insulin...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Kucejova, Blanka, Duarte, Joao, Satapati, Santhosh, Fu, Xiaorong, Ilkayeva, Olga, Newgard, Christopher B., Brugarolas, James, Burgess, Shawn C.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951107/
https://ncbi.nlm.nih.gov/pubmed/27346353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.006
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki