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Improved PCR method for detecting monoclonal immunoglobulin heavy chain rearrangement in B cell neoplasms.
AIMS: To develop a simple, optimised, polymerase chain reaction (PCR) based method for detecting the rearranged immunoglobulin heavy chain (IgH). METHODS: Using as primers oligonucleotides (Fr2A, Fr2B) homologous to the conserved sequences to the framework II region and the joining (JH) region, 25 p...
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| Publicado no: | J Clin Pathol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC495101/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jcp.45.9.770 |
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