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Improved PCR method for detecting monoclonal immunoglobulin heavy chain rearrangement in B cell neoplasms.

AIMS: To develop a simple, optimised, polymerase chain reaction (PCR) based method for detecting the rearranged immunoglobulin heavy chain (IgH). METHODS: Using as primers oligonucleotides (Fr2A, Fr2B) homologous to the conserved sequences to the framework II region and the joining (JH) region, 25 p...

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Detalles Bibliográficos
Publicado en:J Clin Pathol
Autores principales: Ramasamy, I, Brisco, M, Morley, A
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 1992
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC495101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jcp.45.9.770
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