Improved PCR method for detecting monoclonal immunoglobulin heavy chain rearrangement in B cell neoplasms.

AIMS: To develop a simple, optimised, polymerase chain reaction (PCR) based method for detecting the rearranged immunoglobulin heavy chain (IgH). METHODS: Using as primers oligonucleotides (Fr2A, Fr2B) homologous to the conserved sequences to the framework II region and the joining (JH) region, 25 p...

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Main Authors: Ramasamy, I, Brisco, M, Morley, A
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC495101/
https://ncbi.nlm.nih.gov/pubmed/1401205
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