Activation of the JNK-c-Jun pathway in response to irradiation facilitates Fas ligand secretion in hepatoma cells and increases hepatocyte injury

BACKGROUND: It is well established that some irradiated liver non-parenchymal cells secrete pro-inflammatory cytokines to facilitate the development of radiation-induced liver disease. However, little is known on whether the irradiated hepatoma cells-mediated non-irradiated hepatocyte injury occurs...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Dong, Yinying, Shen, Xiaoyun, He, Mingyan, Wu, Zhifeng, Zheng, Qiongdan, Wang, Yaohui, Chen, Yuhan, Wu, Sifan, Cui, Jiefeng, Zeng, Zhaochong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950705/
https://ncbi.nlm.nih.gov/pubmed/27431384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0394-z
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