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DISTINCT FUNCTIONS OF JNK AND C-JUN IN OXIDANT-INDUCED HEPATOCYTE DEATH

Overactivation of c-Jun N-terminal kinase (JNK)/c-Jun signaling is a central mechanism of hepatocyte injury and death including that from oxidative stress. However, the functions of JNK and c-Jun are still unclear, and this pathway also inhibits hepatocyte death. Previous studies of menadione-induce...

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Detalhes bibliográficos
Main Authors: Amir, Muhammad, Liu, Kun, Zhao, Enpeng, Czaja, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636504/
https://ncbi.nlm.nih.gov/pubmed/22644775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24203
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