Conformation-dependent cleavage of staphylococcal nuclease with a disulfide-linked iron chelate.

We report the synthesis and evaluation of (EDTA-2-aminoethyl) 2-pyridyl disulfide. By using this easily prepared cysteine-specific hydrophilic reagent, an ethylenediaminetriacetic acid-Fe3+ complex (EDTA-Fe) was covalently attached to a single genetically engineered cysteine residue in staphylococca...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Ermácora, M R, Delfino, J M, Cuenoud, B, Schepartz, A, Fox, R O
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1992
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631134/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6383
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