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Featured Article: Cardioprotective effects of lysyl oxidase inhibition against volume overload-induced extracellular matrix remodeling

A hallmark of heart failure (HF) is adverse extracellular matrix (ECM) remodeling, which is regulated by the collagen cross-linking enzyme, lysyl oxidase (LOX). In this study, we evaluate the efficacy of LOX inhibition to prevent adverse left ventricular (LV) remodeling and dysfunction using an expe...

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Dades bibliogràfiques
Publicat a:Exp Biol Med (Maywood)
Autors principals: El Hajj, Elia C, El Hajj, Milad C, Ninh, Van K, Gardner, Jason D
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950479/
https://ncbi.nlm.nih.gov/pubmed/26582054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215616511
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