Featured Article: Cardioprotective effects of lysyl oxidase inhibition against volume overload-induced extracellular matrix remodeling

A hallmark of heart failure (HF) is adverse extracellular matrix (ECM) remodeling, which is regulated by the collagen cross-linking enzyme, lysyl oxidase (LOX). In this study, we evaluate the efficacy of LOX inhibition to prevent adverse left ventricular (LV) remodeling and dysfunction using an expe...

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Bibliographic Details
Published in:Exp Biol Med (Maywood)
Main Authors: El Hajj, Elia C, El Hajj, Milad C, Ninh, Van K, Gardner, Jason D
Format: Artigo
Language:Inglês
Published: SAGE Publications 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950479/
https://ncbi.nlm.nih.gov/pubmed/26582054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215616511
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