Resveratrol attenuated TNF-α–induced MMP-3 expression in human nucleus pulposus cells by activating autophagy via AMPK/SIRT1 signaling pathway

Resveratrol (RSV) is known to play a role of anti-TNF-α in a number of cell types. However, whether RSV modulates the effects of TNF-α on human nucleus pulposus (NP) cells is unknown. The purpose of this study is to investigate whether RSV regulates TNF-α–induced matrix metalloproteinase-3 (MMP-3) e...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Wang, Xiao-Hu, Zhu, Lei, Hong, Xin, Wang, Yun-Tao, Wang, Feng, Bao, Jun-Ping, Xie, Xin-Hui, Liu, Lei, Wu, Xiao-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950401/
https://ncbi.nlm.nih.gov/pubmed/26946533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216637940
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