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Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase

Cancer cell detachment from the primary tumor site represents the first stage of metastasis. Previous studies have identified that cell detachment is triggered by cytoskeletal disruption, which may induce a wide variety of cellular changes. Focal adhesion kinase (FAK) exhibits crucial cellular funct...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Fan, Yibo, Qu, Xiujuan, Ma, Yanju, Liu, Yunpeng, Hu, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950184/
https://ncbi.nlm.nih.gov/pubmed/27446403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4730
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