DR5‐Cbl‐b/c‐Cbl‐TRAF2 complex inhibits TRAIL‐induced apoptosis by promoting TRAF2‐mediated polyubiquitination of caspase‐8 in gastric cancer cells

Ubiquitination of caspase‐8 regulates TNF‐related apoptosis‐inducing ligand (TRAIL) sensitivity in cancer cells, and the preligand assembly complex plays a role in caspase‐8 polyubiquitination. However, whether such a complex exists in gastric cancer cells and its role in TRAIL‐triggered apoptosis i...

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Detaylı Bibliyografya
Yayımlandı:Mol Oncol
Asıl Yazarlar: Xu, Ling, Zhang, Ye, Qu, Xiujuan, Che, Xiaofang, Guo, Tianshu, Li, Ce, Ma, Rui, Fan, Yibo, Ma, Yanju, Hou, Kezuo, Li, Danni, Hu, Xuejun, Liu, Bofang, Yu, Ruoxi, Yan, Hongfei, Gong, Jing, Liu, Yunpeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709619/
https://ncbi.nlm.nih.gov/pubmed/28972304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12140
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