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Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase
Cancer cell detachment from the primary tumor site represents the first stage of metastasis. Previous studies have identified that cell detachment is triggered by cytoskeletal disruption, which may induce a wide variety of cellular changes. Focal adhesion kinase (FAK) exhibits crucial cellular funct...
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| Publié dans: | Oncol Lett |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
D.A. Spandidos
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4950184/ https://ncbi.nlm.nih.gov/pubmed/27446403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4730 |
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