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Regulating telomere length from the inside out: the replication fork model

Telomere length is regulated around an equilibrium set point. Telomeres shorten during replication and are lengthened by telomerase. Disruption of the length equilibrium leads to disease; thus, it is important to understand the mechanisms that regulate length at the molecular level. The prevailing p...

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Detalhes bibliográficos
Publicado no:Genes Dev
Autor principal: Greider, Carol W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949321/
https://ncbi.nlm.nih.gov/pubmed/27401551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.280578.116
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