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Regulating telomere length from the inside out: the replication fork model

Telomere length is regulated around an equilibrium set point. Telomeres shorten during replication and are lengthened by telomerase. Disruption of the length equilibrium leads to disease; thus, it is important to understand the mechanisms that regulate length at the molecular level. The prevailing p...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autore principale: Greider, Carol W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949321/
https://ncbi.nlm.nih.gov/pubmed/27401551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.280578.116
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