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New Bifunctional Chelator p-SCN-PhPr-NE3TA for Copper-64: Synthesis, Peptidomimetic Conjugation, Radiolabeling, and Evaluation for PET Imaging

Bifunctional chelators play an important role in developing metallic radionuclide-based radiopharmaceuticals. In this study, a new bifunctional ligand, p-SCN-PhPr-NE3TA, was synthesized and conjugated to a very late antigen-4 targeting peptidomimetic, LLP2A, for evaluating its application in (64)Cu-...

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Detalles Bibliográficos
Publicado en:Inorg Chem
Main Authors: Gai, Yongkang, Sun, Lingyi, Hui, Wenqi, Ouyang, Qin, Anderson, Carolyn J., Xiang, Guangya, Ma, Xiang, Zeng, Dexing
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949121/
https://ncbi.nlm.nih.gov/pubmed/27347690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.6b00395
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