Improved Synthesis of the Bifunctional Chelator p-SCN-Bn-HOPO

The bifunctional ligand p-SCN-Bn-HOPO, which has four 1,2-hydroxypyridinone groups on a spermine backbone with an isothiocyanate linker, has been shown to be an efficient and stable chelator for Zr(IV) and, more importantly, the radioisotope (89)Zr for use in radiolabeling antibodies for positron em...

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Detalles Bibliográficos
Publicado en:Org Biomol Chem
Main Authors: Bhupathiraju, N. V. S. Dinesh K., Younes, Ali, Cao, Minhua, Ali, Jafar, Cicek, Huseyin T., Tully, Kathryn M., Ponnala, Shashikanth, Babich, John W., Deri, Melissa A., Lewis, Jason S., Francesconi, Lynn C., Drain, Charles Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640124/
https://ncbi.nlm.nih.gov/pubmed/31268109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob01068h
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