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Improved Synthesis of the Bifunctional Chelator p-SCN-Bn-HOPO

The bifunctional ligand p-SCN-Bn-HOPO, which has four 1,2-hydroxypyridinone groups on a spermine backbone with an isothiocyanate linker, has been shown to be an efficient and stable chelator for Zr(IV) and, more importantly, the radioisotope (89)Zr for use in radiolabeling antibodies for positron em...

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Bibliografiske detaljer
Udgivet i:Org Biomol Chem
Main Authors: Bhupathiraju, N. V. S. Dinesh K., Younes, Ali, Cao, Minhua, Ali, Jafar, Cicek, Huseyin T., Tully, Kathryn M., Ponnala, Shashikanth, Babich, John W., Deri, Melissa A., Lewis, Jason S., Francesconi, Lynn C., Drain, Charles Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640124/
https://ncbi.nlm.nih.gov/pubmed/31268109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob01068h
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