Improved Synthesis of the Bifunctional Chelator p-SCN-Bn-HOPO

The bifunctional ligand p-SCN-Bn-HOPO, which has four 1,2-hydroxypyridinone groups on a spermine backbone with an isothiocyanate linker, has been shown to be an efficient and stable chelator for Zr(IV) and, more importantly, the radioisotope (89)Zr for use in radiolabeling antibodies for positron em...

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Publié dans:Org Biomol Chem
Auteurs principaux: Bhupathiraju, N. V. S. Dinesh K., Younes, Ali, Cao, Minhua, Ali, Jafar, Cicek, Huseyin T., Tully, Kathryn M., Ponnala, Shashikanth, Babich, John W., Deri, Melissa A., Lewis, Jason S., Francesconi, Lynn C., Drain, Charles Michael
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640124/
https://ncbi.nlm.nih.gov/pubmed/31268109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob01068h
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