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Tumor Necrosis Factor α–Dependent Proinflammatory Gene Induction Is Inhibited by Cyclic Tensile Strain in Articular Chondrocytes In Vitro
OBJECTIVE: To understand the intracellular mechanisms of the action of mechanical strain on articular chondrocytes during inflammation. METHODS: One of the major mediators responsible for cartilage destruction in inflamed articular joints is tumor necrosis factor α (TNFα). Therefore, in this study w...
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| Udgivet i: | Arthritis Rheum |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4948993/ https://ncbi.nlm.nih.gov/pubmed/11665971 |
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