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Tumor Necrosis Factor α–Dependent Proinflammatory Gene Induction Is Inhibited by Cyclic Tensile Strain in Articular Chondrocytes In Vitro

OBJECTIVE: To understand the intracellular mechanisms of the action of mechanical strain on articular chondrocytes during inflammation. METHODS: One of the major mediators responsible for cartilage destruction in inflamed articular joints is tumor necrosis factor α (TNFα). Therefore, in this study w...

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Publicat a:Arthritis Rheum
Autors principals: Long, Ping, Gassner, Robert, Agarwal, Sudha
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948993/
https://ncbi.nlm.nih.gov/pubmed/11665971
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