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Tumor Necrosis Factor α–Dependent Proinflammatory Gene Induction Is Inhibited by Cyclic Tensile Strain in Articular Chondrocytes In Vitro

OBJECTIVE: To understand the intracellular mechanisms of the action of mechanical strain on articular chondrocytes during inflammation. METHODS: One of the major mediators responsible for cartilage destruction in inflamed articular joints is tumor necrosis factor α (TNFα). Therefore, in this study w...

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Detalles Bibliográficos
Publicado en:Arthritis Rheum
Main Authors: Long, Ping, Gassner, Robert, Agarwal, Sudha
Formato: Artigo
Idioma:Inglês
Publicado: 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948993/
https://ncbi.nlm.nih.gov/pubmed/11665971
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