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Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells

Although the possibility of developing cardiac steroids/cardiac glycosides as novel cancer therapeutic agents has been recognized, the mechanism of their anticancer activity is still not clear enough. Toad venom extract containing bufadienolides, which belong to cardiac steroids, has actually long b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yue, Qingxi, Zhen, Hong, Huang, Ming, Zheng, Xi, Feng, Lixing, Jiang, Baohong, Yang, Min, Wu, Wanying, Liu, Xuan, Guo, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948917/
https://ncbi.nlm.nih.gov/pubmed/27428326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159034
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