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Essential role of autophagy in fucoxanthin-induced cytotoxicity to human epithelial cervical cancer HeLa cells

AIM: To investigate the effects and the molecular mechanisms of fucoxanthin, a major carotenoid found in edible seaweed, on HeLa cells. METHODS: The cytotoxicity of fucoxanthin was evaluated using MTT assay. Cell cycle and apoptosis were evaluated using flow cytometric analysis. Autophagy was detect...

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Detalhes bibliográficos
Main Authors: Hou, Li-li, Gao, Chao, Chen, Liang, Hu, Guo-qiang, Xie, Song-qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006467/
https://ncbi.nlm.nih.gov/pubmed/23974517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.90
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