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Proteomic Analysis Revealed the Important Role of Vimentin in Human Cervical Carcinoma HeLa Cells Treated With Gambogic Acid

Gambogic acid (GA) is an anticancer agent in phase IIb clinical trial in China. In HeLa cells, GA inhibited cell proliferation, induced cell cycle arrest at G2/M phase and apoptosis, as showed by results of MTT assay and flow cytometric analysis. Possible target-related proteins of GA were searched...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Yue, Qingxi, Feng, Lixing, Cao, Biyin, Liu, Miao, Zhang, Dongmei, Wu, Wanying, Jiang, Baohong, Yang, Min, Liu, Xuan, Guo, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762520/
https://ncbi.nlm.nih.gov/pubmed/26499837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.053272
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