Interleukin-32α inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial–mesenchymal transition, invasion, and metastasis in pancreatic cancer cells

Interleukin (IL)-32 is a newly discovered cytokine that has multifaceted roles in inflammatory bowel disease, cancer, and autoimmune diseases and participates in cell apoptosis, cancer cell growth inhibition, accentuation of inflammation, and angiogenesis. Here, we investigated the potential effects...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Chen, Jingfeng, Wang, Silu, Su, Jiadong, Chu, Guanyu, You, Heyi, Chen, Zongjing, Sun, Hongwei, Chen, Bicheng, Zhou, Mengtao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948719/
https://ncbi.nlm.nih.gov/pubmed/27471397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S103581
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