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The involvement of JAK-STAT3 in cell motility, invasion, and metastasis

JAK-STAT3 signaling, while regulating many aspects of cancer development and progression, promotes invasion and metastasis through activation of key metastasis promoting genes such as WASF3. STAT3 promotes WASF3 expression and JAK2 independently activates it, which is required for invasion. JAK-STAT...

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Detalhes bibliográficos
Main Authors: Teng, Yong, Ross, James L, Cowell, John K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995737/
https://ncbi.nlm.nih.gov/pubmed/24778926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.28086
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