SHANK3 controls maturation of social reward circuits in the VTA

Haploinsufficiency of SHANK3, encoding the synapse scaffolding protein SHANK3, leads to a highly penetrant form of Autism Spectrum Disorder (ASD). How SHANK3 insufficiency affects specific neural circuits and this is related to specific ASD symptoms remains elusive. Here we used shRNA to model Shank...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Neurosci
Main Authors: Bariselli, Sebastiano, Tzanoulinou, Stamatina, Glangetas, Christelle, Prévost-Solié, Clément, Pucci, Luca, Viguié, Joanna, Bezzi, Paola, O’Connor, Eoin C., Georges, François, Lüscher, Christian, Bellone, Camilla
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948673/
https://ncbi.nlm.nih.gov/pubmed/27273769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4319
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker