Loss of H3K27 tri-methylation is a diagnostic marker for Malignant Peripheral Nerve Sheath Tumors and an indicator for an inferior survival

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that can show overlapping features with benign neurofibromas as well as high-grade sarcomas. Additional diagnostic markers are needed to aid in this often challenging differential diagnosis. Recently mutations in two critical...

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Publicado no:Mod Pathol
Main Authors: Cleven, Arjen H.G., Al Sannaa, Ghadah A., Bruijn, Inge Briaire-de, Ingram, Davis R., van de Rijn, Matt, Rubin, Brian P., de Vries, Maurits, Watson, Kelsey, Torres, Keila E., Wang, Wei-Lien, van Duinen, Sjoerd, Hogendoorn, Pancras C. W., Lazar, Alexander J., Bovée, Judith V.M.G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948583/
https://ncbi.nlm.nih.gov/pubmed/26990975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2016.45
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