Opening the archives for state of the art tumour genetic research: sample processing for array-CGH using decalcified, formalin-fixed, paraffin-embedded tissue-derived DNA samples

BACKGROUND: Molecular genetic studies on rare tumour entities, such as bone tumours, often require the use of decalcified, formalin-fixed, paraffin-embedded tissue (dFFPE) samples. Regardless of which decalcification procedure is used, this introduces a vast breakdown of DNA that precludes the possi...

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Bibliografiske detaljer
Main Authors: de Jong, Danielle, Verbeke, Sofie LJ, Meijer, Danielle, Hogendoorn, Pancras CW, Bovee, Judith VMG, Szuhai, Károly
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Technical Note
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024235/
https://ncbi.nlm.nih.gov/pubmed/21205301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-1
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