Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling

Scaffolding proteins organize the information flow from activated G protein-coupled receptors (GPCRs) to intracellular effector cascades both spatially and temporally. By this means, signaling scaffolds, such as A-kinase anchoring proteins (AKAPs), compartmentalize kinase activity and ensure substra...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bachmann, Verena A., Mayrhofer, Johanna E., Ilouz, Ronit, Tschaikner, Philipp, Raffeiner, Philipp, Röck, Ruth, Courcelles, Mathieu, Apelt, Federico, Lu, Tsan-Wen, Baillie, George S., Thibault, Pierre, Aanstad, Pia, Stelzl, Ulrich, Taylor, Susan S., Stefan, Eduard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948347/
https://ncbi.nlm.nih.gov/pubmed/27357676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608061113
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