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Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

Although regulation of energy metabolism has been linked with multiple disorders, its role in depression and responsiveness to antidepressants is less known. We found that an epigenetic and energetic agent, acetyl-l-carnitine (LAC, oral administration), rapidly rescued the depressive- and central an...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Bigio, Benedetta, Mathé, Aleksander A., Sousa, Vasco C., Zelli, Danielle, Svenningsson, Per, McEwen, Bruce S., Nasca, Carla
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948346/
https://ncbi.nlm.nih.gov/pubmed/27354525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603111113
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