Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

Although regulation of energy metabolism has been linked with multiple disorders, its role in depression and responsiveness to antidepressants is less known. We found that an epigenetic and energetic agent, acetyl-l-carnitine (LAC, oral administration), rapidly rescued the depressive- and central an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Bigio, Benedetta, Mathé, Aleksander A., Sousa, Vasco C., Zelli, Danielle, Svenningsson, Per, McEwen, Bruce S., Nasca, Carla
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948346/
https://ncbi.nlm.nih.gov/pubmed/27354525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603111113
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