Solid tumor therapy by selectively targeting stromal endothelial cells

Engineered tumor-targeted anthrax lethal toxin proteins have been shown to strongly suppress growth of solid tumors in mice. These toxins work through the native toxin receptors tumor endothelium marker-8 and capillary morphogenesis protein-2 (CMG2), which, in other contexts, have been described as...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Liu, Shihui, Liu, Jie, Ma, Qian, Cao, Liu, Fattah, Rasem J., Yu, Zuxi, Bugge, Thomas H., Finkel, Toren, Leppla, Stephen H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948345/
https://ncbi.nlm.nih.gov/pubmed/27357689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600982113
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