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Recombinant Expression and Purification of a Tumor-Targeted Toxin in Bacillus anthracis

Many recombinant therapeutic proteins are purified from Escherichia coli. While expression in E. coli is easily achieved, some disadvantages such as protein aggregation, formation of inclusion bodies, and contamination of purified proteins with the lipopolysaccharides arise. Lipopolysaccharides have...

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Detalhes bibliográficos
Main Authors: Bachran, Christopher, Abdelazim, Suzanne, Fattah, Rasem J., Liu, Shihui, Leppla, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545075/
https://ncbi.nlm.nih.gov/pubmed/23200832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.11.055
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