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Solid tumor therapy by selectively targeting stromal endothelial cells
Engineered tumor-targeted anthrax lethal toxin proteins have been shown to strongly suppress growth of solid tumors in mice. These toxins work through the native toxin receptors tumor endothelium marker-8 and capillary morphogenesis protein-2 (CMG2), which, in other contexts, have been described as...
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Udgivet i: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
National Academy of Sciences
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4948345/ https://ncbi.nlm.nih.gov/pubmed/27357689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600982113 |
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