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Enzyme surface rigidity tunes the temperature dependence of catalytic rates

The structural origin of enzyme adaptation to low temperature, allowing efficient catalysis of chemical reactions even near the freezing point of water, remains a fundamental puzzle in biocatalysis. A remarkable universal fingerprint shared by all cold-active enzymes is a reduction of the activation...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Isaksen, Geir Villy, Åqvist, Johan, Brandsdal, Bjørn Olav
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948340/
https://ncbi.nlm.nih.gov/pubmed/27354533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605237113
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