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Enzyme surface rigidity tunes the temperature dependence of catalytic rates

The structural origin of enzyme adaptation to low temperature, allowing efficient catalysis of chemical reactions even near the freezing point of water, remains a fundamental puzzle in biocatalysis. A remarkable universal fingerprint shared by all cold-active enzymes is a reduction of the activation...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Isaksen, Geir Villy, Åqvist, Johan, Brandsdal, Bjørn Olav
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948340/
https://ncbi.nlm.nih.gov/pubmed/27354533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605237113
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