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Modular elements of the TPR domain in the Mps1 N terminus differentially target Mps1 to the centrosome and kinetochore

Faithful segregation of chromosomes to two daughter cells is regulated by the formation of a bipolar mitotic spindle and the spindle assembly checkpoint, ensuring proper spindle function. Here we show that the proper localization of the kinase Mps1 (monopolar spindle 1) is critical to both these pro...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Marquardt, Joseph R., Perkins, Jennifer L., Beuoy, Kyle J., Fisk, Harold A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948323/
https://ncbi.nlm.nih.gov/pubmed/27339139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607421113
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