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Histone deacetylase inhibition reveals a tumor-suppressive function of MYC-regulated miRNA in breast and lung carcinoma

Histone deacetylase (HDAC) inhibition leads to dynamic changes in the epigenetic landscape that is postulated to alter the expression of critical mediators of cellular proliferation and death. While current HDAC inhibitors have shown to be efficacious in the treatment of specific hematologic maligna...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Adams, C M, Eischen, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947678/
https://ncbi.nlm.nih.gov/pubmed/26915294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.9
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