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Histone deacetylase inhibition reveals a tumor-suppressive function of MYC-regulated miRNA in breast and lung carcinoma

Histone deacetylase (HDAC) inhibition leads to dynamic changes in the epigenetic landscape that is postulated to alter the expression of critical mediators of cellular proliferation and death. While current HDAC inhibitors have shown to be efficacious in the treatment of specific hematologic maligna...

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Publicat a:Cell Death Differ
Autors principals: Adams, C M, Eischen, C M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947678/
https://ncbi.nlm.nih.gov/pubmed/26915294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.9
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