Differential localization of A-Raf regulates MST2-mediated apoptosis during epithelial differentiation

A-Raf belongs to the family of oncogenic Raf kinases that are involved in mitogenic signaling by activating the MEK-ERK pathway. Low kinase activity of A-Raf toward MEK suggested that A-Raf might have alternative functions. We recently identified A-Raf as a potent inhibitor of the proapoptotic mamma...

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Опубликовано в: :Cell Death Differ
Главные авторы: Rauch, J, Vandamme, D, Mack, B, McCann, B, Volinsky, N, Blanco, A, Gires, O, Kolch, W
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947672/
https://ncbi.nlm.nih.gov/pubmed/26891695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.2
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