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Differential localization of A-Raf regulates MST2-mediated apoptosis during epithelial differentiation
A-Raf belongs to the family of oncogenic Raf kinases that are involved in mitogenic signaling by activating the MEK-ERK pathway. Low kinase activity of A-Raf toward MEK suggested that A-Raf might have alternative functions. We recently identified A-Raf as a potent inhibitor of the proapoptotic mamma...
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| Vydáno v: | Cell Death Differ |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947672/ https://ncbi.nlm.nih.gov/pubmed/26891695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.2 |
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