TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma

Advances made in pancreatic cancer therapy have been far from sufficient and have allowed only a slight improvement in global survival of patients with pancreatic ductal adenocarcinoma (PDA). Recent progresses in chemotherapy have offered some hope for an otherwise gloomy outlook, however, only a li...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Thakur, A K, Nigri, J, Lac, S, Leca, J, Bressy, C, Berthezene, P, Bartholin, L, Chan, P, Calvo, E, Iovanna, J L, Vasseur, S, Guillaumond, F, Tomasini, R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947667/
https://ncbi.nlm.nih.gov/pubmed/26943320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.18
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