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TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses

The multiple isoforms of p73, a member of the p53 family, share the ability to modulate p53 activities but also have unique properties, leading to a complex and poorly understood functional network. In vivo, p73 isoforms have been implicated in tumor suppression (TAp73(−/−) mice), DNA damage (ΔNp73(...

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Detalhes bibliográficos
Main Authors: Tomasini, R, Secq, V, Pouyet, L, Thakur, A K, Wilhelm, M, Nigri, J, Vasseur, S, Berthezene, P, Calvo, E, Melino, G, Mak, T W, Iovanna, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554333/
https://ncbi.nlm.nih.gov/pubmed/22976836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.123
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