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TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses
The multiple isoforms of p73, a member of the p53 family, share the ability to modulate p53 activities but also have unique properties, leading to a complex and poorly understood functional network. In vivo, p73 isoforms have been implicated in tumor suppression (TAp73(−/−) mice), DNA damage (ΔNp73(...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554333/ https://ncbi.nlm.nih.gov/pubmed/22976836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.123 |
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