Targeted oncogene activation by site-specific recombination in transgenic mice.

An efficient and accurate method for controlled in vivo transgene modulation by site-directed recombination is described. Seven transgenic mouse founder lines were produced carrying the murine lens-specific alpha A-crystallin promoter and the simian virus 40 large tumor-antigen gene sequence, separa...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lakso, M, Sauer, B, Mosinger, B, Lee, E J, Manning, R W, Yu, S H, Mulder, K L, Westphal, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6232
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