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Targeted oncogene activation by site-specific recombination in transgenic mice.

An efficient and accurate method for controlled in vivo transgene modulation by site-directed recombination is described. Seven transgenic mouse founder lines were produced carrying the murine lens-specific alpha A-crystallin promoter and the simian virus 40 large tumor-antigen gene sequence, separa...

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Bibliografiske detaljer
Main Authors: Lakso, M, Sauer, B, Mosinger, B, Lee, E J, Manning, R W, Yu, S H, Mulder, K L, Westphal, H
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49474/
https://ncbi.nlm.nih.gov/pubmed/1631115
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