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Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression

Interferon gamma (IFN-γ) is an essential mediator of host defense against intracellular pathogens, including the protozoan parasite Toxoplasma gondii. However, prior T. gondii infection blocks IFN-γ-dependent gene transcription, despite the downstream transcriptional activator STAT1 being activated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Host Microbe
Egile Nagusiak: Olias, Philipp, Etheridge, Ronald D., Zhang, Yong, Holtzman, Michael J., Sibley, L. David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947229/
https://ncbi.nlm.nih.gov/pubmed/27414498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.06.006
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