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A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells

Thousands of long noncoding RNA (lncRNA) genes are encoded in the human genome, and hundreds of them are evolutionarily conserved, but their functions and modes of action remain largely obscure. Particularly enigmatic lncRNAs are those that are exported to the cytoplasm, including NORAD—an abundant...

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Vydáno v:Nat Commun
Hlavní autoři: Tichon, Ailone, Gil, Noa, Lubelsky, Yoav, Havkin Solomon, Tal, Lemze, Doron, Itzkovitz, Shalev, Stern-Ginossar, Noam, Ulitsky, Igor
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947167/
https://ncbi.nlm.nih.gov/pubmed/27406171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12209
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