Global mRNA polarization regulates translation efficiency in the intestinal epithelium

Asymmetric messenger RNA (mRNA) localization facilitates efficient translation in cells such as neurons and fibroblasts. However, the extent and importance of mRNA polarization in epithelial tissues are unclear. Here, we used single-molecule transcript imaging and subcellular transcriptomics to unco...

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Vydáno v:Science
Hlavní autoři: Moor, Andreas E., Golan, Matan, Massasa, Efi E., Lemze, Doron, Weizman, Tomer, Shenhav, Rom, Baydatch, Shaked, Mizrahi, Orel, Winkler, Roni, Golani, Ofra, Stern-Ginossar, Noam, Itzkovitz, Shalev
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955215/
https://ncbi.nlm.nih.gov/pubmed/28798045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan2399
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