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Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells

Long noncoding RNAs (lncRNAs) are emerging as key players in multiple cellular pathways1, but their modes of action, and how those are dictated by sequence remain elusive. lncRNAs tend to be enriched in the nuclear fraction, whereas most mRNAs are overtly cytoplasmic2, although several studies have...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Lubelsky, Yoav, Ulitsky, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047738/
https://ncbi.nlm.nih.gov/pubmed/29466324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25757
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