The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity

Identification of positive regulators of T-cell immunity induced during autoimmune diseases is critical for developing novel therapies. The endoplasmic reticulum resident ubiquitin ligase Hrd1 has recently emerged as a critical regulator of dendritic cell antigen presentation, but its role in T-cell...

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Vydáno v:Nat Commun
Hlavní autoři: Xu, Yuanming, Zhao, Fang, Qiu, Quan, Chen, Kun, Wei, Juncheng, Kong, Qingfei, Gao, Beixue, Melo-Cardenas, Johanna, Zhang, Bin, Zhang, Jinping, Song, Jianxun, Zhang, Donna D., Zhang, Jianing, Fan, Yunping, Li, Huabin, Fang, Deyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947160/
https://ncbi.nlm.nih.gov/pubmed/27417417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12073
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