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Oncofetal Epigenetic Bivalency in Breast Cancer Cells: H3K4 and H3K27 Tri-Methylation as a Biomarker for Phenotypic Plasticity

Alterations in the epigenetic landscape are fundamental drivers of aberrant gene expression that contribute to cancer progression and pathology. Understanding specific modes of epigenetic regulation can be used to identify novel biomarkers or targets for therapeutic intervention to clinically treat...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Messier, Terri L., Boyd, Joseph R., Gordon, Jonathan A. R., Stein, Janet L., Lian, Jane B., Stein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946968/
https://ncbi.nlm.nih.gov/pubmed/26916849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25359
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